Seq-Well S^3 Released

Seq-Well S^3 Released

Oct 13, 2020

Our improvements to the Seq-Well scRNA-seq platform were release today – read the publication in Immunity here and the press release here.

Constantine Named 2020 Hertz Fellow!

Constantine Named 2020 Hertz Fellow!

May 20, 2020

Our very own Constantine Tzouanas has been named a 2020 Hertz Fellow! We’re very excited for this achievement, and looking forward to what’s in store. Read more about the Hertz Fellowship and Constantine here.

Partnership with Chan Zuckerberg Initiative to Profile Pediatric COVID-19 Announced

Partnership with Chan Zuckerberg Initiative to Profile Pediatric COVID-19 Announced

May 06, 2020

With Boston Children’s Hospital PI (and former post-doc!) Jose Ordovas-Montanes, we will expand our COVID-19-related research to include understanding disease pathogenesis in a pediatric cohort – the data and findings of which will be readily accessible to the scientific community. Learn more about our and others’ efforts from CZI here and about single-cell genomics in […]

Alex Wins Edgerton Faculty Award!

Alex Wins Edgerton Faculty Award!

Apr 23, 2020

Congratulations to Alex for winning the 2019-2020 Harold E. Edgerton Faculty Achievement Award, given for “his leadership and pioneering spirit; his vision, inventiveness, and enthusiasm for mentorship and collaboration; and his tremendous contributions to a critical area at the intersection of science and medicine.” Read about the award and Alex here.

Study Describing ACE2 as an Interferon-Stimulated Gene Out in Cell

Study Describing ACE2 as an Interferon-Stimulated Gene Out in Cell

Apr 21, 2020

Our study showing ACE2, the entry receptor for SARS-CoV-2, as an interferon-stimulated gene is now out in Cell here. Read about the study in The Boston Globe and MIT News, C&EN, NIH Director’s blog, among others. Datasets analyzed in this study are described here and can be downloaded from our single-cell portal here. We hope […]

COVID-19 scRNA-seq Resource Datasets Released

COVID-19 scRNA-seq Resource Datasets Released

Mar 14, 2020

In light of the spread of SARS-CoV-2, we are sharing multiple unpublished and published scRNA-seq datasets across both health and disease that harbor cells expressing ACE2 (the gene encoding the host receptor) and TMPRSS2 (the gene involved in processing the viral spike protein). We are sharing these resources for SARS-CoV-2 on the Alexandria Project. This […]

New Study on Increased TB Vaccine Efficacy Now Out

New Study on Increased TB Vaccine Efficacy Now Out

Jan 02, 2020

Our paper on increased tuberculosis (TB) vaccine efficacy with intravenous injection in nonhuman primates is now out in Nature. With collaborators at the National Institutes of Health’s National Institute of Allergy and Infectious Diseases and others, we show greatly enhanced immune protection and outcome compared to traditional intradermal injection of the TB vaccine BCG, which […]