Jose is a second-year Postdoctoral Fellow in the Shalek lab where he is interested in utilizing single-cell genomics to understand the organizing principles of mucosal barrier tissues in health and how to re-balance them in disease. Jose’s research specifically looks at the human gastrointestinal tract and respiratory airways in inflammatory and allergic states, respectively.

Jose grew up in the Boston area, circling the perimeter with high school in Framingham, MA, college at Tufts University, and graduate studies in the Harvard Immunology program. During his undergraduate, Jose worked in human immunology labs at Biogen Idec, University College London, and Children’s Hospital Boston where he focused on monogenic immune deficiencies. For his PhD work, Jose trained with Uli von Andrian studying how the nervous system and the immune system function together as the principal sensory interfaces between the internal and external environment. Due to his problem of reading too much, realizing that this only covered two broad classes of cells, and wanting to return to the human system, he decided to take the plunge into the field of single cell genomics to be able to work on all cell types all the time. Jose is a recently retired amateur bike racer and a perpetually amateur chef.

Reduced cellular diversity and an altered basal progenitor cell state inform epithelial barrier dysfunction in human type 2 immunity
  • Jose Ordovas-Montanes et al.,
  • BioRxiv,
  • 2017
  • Medicine
  • Cell Atlas
  • Immunology
  • José Ordovas-Montañes
  • Sarah Nyquist
  • Marc Wadsworth
  • Travis Hughes
  • Sam Kazer
  • Alex K. Shalek