Carly’s data visualization of SHIV infection in rhesus macaques (previously lauded here and here) has been selected as one of the best science images of 2019 by the Nature news team. Read about it here....
Our recent paper details a strategy, co-developed with the Love Lab at MIT, for pairing TCR sequencing with whole-transcriptome profiling in single-cells via 3′-barcoded techniques. Using a targeted pulldown and amplification method, we are able to sequence TCR CDR3 regions...
We’re stoked to have this paper up! We present our work finding new roles for sensory neurons within inflammatory responses and previously unappreciated axes of neuro-immune crosstalk. Led by Shalek lab MD-PhD student Carly Ziegler and post doc Tracy Huang...
Alex was recently featured in Nature Methods to discuss challenges and future opportunities in high-throughput genomics techniques. He joins researchers spanning across the spectrum of biology disciplines in laying out technological challenges of their respective fields and the great potential...
Alex was recently in Sao Paulo to kick off work with the the Human Cell Atlas in Latin America. Alongside both Brazilian and international researchers, Alex introduced the scope and potential impact of the initiative, which seeks to create comprehensive reference...
Congratulations to Kellie Kolb, the first student from the Shalek Lab to receive her PhD! We wish Kellie the best of luck in her future endeavors, and we’re excited for many more graduations in the coming years!...
A recent paper published in Nature from the Shalek lab and collaborators was featured in NIH News. Ardain et. al. demonstrate that group 3 innate lymphoid cells localize to the lungs soon after M. tuberculosis infection, providing an early line...
Carly’s data visualization from a non-human primate atlas is one of 28 entries from 12 countries shortlisted for the Wellcome Photography Prize 2019. The overall winner will be announced on 3 July 2019. Learn more at the following link....
Alex was recently made an Institute Member at the Broad. Visit the link to see the full list of Institute Members....
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Immunity celebrates its 25th anniversary at an exciting time in immunology, marked by the advent of new, door-opening approaches and a deeper understanding of the centrality of the immune system to both health and disease. Alex is among 25 investigators...
Carly’s visualization of single-cell mRNA sequencing data of 45,782 cells from 14 organs was selected in the 2019 Koch Institute Image Awards. Carly’s image and the other 9 awardees are featured in Stat News. Congratulations Carly!...
The Shalek Lab is featured in the Immunity 25th Anniversary Photo Gallery. ...
Alex K. Shalek has been approved for promotion to Associate Professor without Tenure! The official promotion will be effective July 1. Congratulations Alex! Alex’s research is directed towards the creation and implementation of new technologies to understand how cells collectively...
Our work combining microfluidic identification of circulating tumor cells (CTCs) and single-cell profiling is currently highlighted on MIT News, while the forthcoming paper is set to appear in the Jan. 21 issue of PNAS. This work represents an ongoing collaboration...