Our study of untreated HIV-1 infection is now out in Nature Medicine! We profile longitudinal peripheral blood samples from pre-infection through chronic infection to characterize gene programs that are temporally-correlated in and between cell types. Read the press release here....
Pre-print Detailing ACE2 as an Interferon-Stimulated Gene Now Available
Our pre-print work detailing ACE2 upregulation in response to interferons, and type I interferons in particular, is now available here. Descriptions of the datasets analyzed in the study are found here on our COVID-19 Resource page, along with links to...
COVID-19 scRNA-seq Resource Datasets Released
In light of the spread of SARS-CoV-2, we are sharing multiple unpublished and published scRNA-seq datasets across both health and disease that harbor cells expressing ACE2 (the gene encoding the host receptor) and TMPRSS2 (the gene involved in processing the...
Marc Wadsworth Graduates from the Shalek Lab!
A belated congratulations to Marc Wadsworth for successfully defending his thesis! We wish Marc the best of luck in his future endeavors, and we’re excited for all the upcoming defenses this semester!...
TB Vaccine Efficacy Study Previewed in Cell
Our recent publication on increased tuberculosis vaccine efficacy via alternative administration routes is previewed here in Cell. Read the paper here....