Biography

Toby Aicher is a research technician in the Shalek and the Walker labs who uses single-cell RNA-sequencing to investigate how the immune system responds to acute HIV infection in elite controllers and chronic progressors. His interests include developmental trajectories of lymphocytes, functional heterogeneity among cytotoxic T-cells, and epigenomics.  
Toby grew up in Maine and attended college in Vermont. He has a B.A. in Molecular Biology and Biochemistry from Middlebury College. In his free time Toby likes swimming, amateur astronomy, and exploring Boston.

Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation
  • Kummerlowe et al.,
  • Science Translational Medicine,
  • 2022
  • Microbiology
  • Genomics
  • Immunology
  • Biology
  • Cell Atlas
  • Infectious Disease
  • Conner Kummerlowe
  • Travis Hughes
  • Nolawit Mulugeta
  • Ira Fleming
  • Marko Vukovic
  • Benjamin Doran
  • Toby Aicher
  • Marc Wadsworth II
  • José Ordovas-Montañes
  • Alex K. Shalek
Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection
  • Kazer et al.,
  • Nature Medicine,
  • 2020
  • Infectious Disease
  • Genomics
  • Biology
  • Statistics
  • Computational Methods
  • Immunology
  • Sam Kazer
  • Toby Aicher
  • Shaina Carroll
  • José Ordovas-Montañes
  • Vincent Miao
  • Carly Ziegler
  • Sarah Nyquist
  • Alex K. Shalek
Induction of metabolic quiescence defines the transitional to follicular B cell switch
  • Farmer et al.,
  • Science Signaling,
  • 2019
  • Biology
  • Genomics
  • Immunology
  • Toby Aicher
  • Alex K. Shalek
Integrated Single-Cell Analysis of Multicellular Immune Dynamics during Hyper-Acute HIV-1 Infection
  • Kazer S.W. et al.,
  • bioRxiv,
  • 2019
  • Biology
  • Genomics
  • Immunology
  • Infectious Disease
  • Sam Kazer
  • Toby Aicher
  • Shaina Carroll
  • José Ordovas-Montañes
  • Carly Ziegler
  • Sarah Nyquist
  • Alex K. Shalek
Seq-Well: A Sample-Efficient, Portable Picowell Platform for Massively Parallel Single-Cell RNA Sequencing
  • Aicher et al.,
  • Single-Cell Methods,
  • 2019
  • R&D
  • Technology
  • Toby Aicher
  • Shaina Carroll
  • Marc Wadsworth II
  • Travis Hughes
  • Alex K. Shalek