Degrees & Affiliations
BS, Chemical & Biological Engineering - University of Colorado Boulder PhD, Medical Engineering & Medical Physics - Harvard-MIT Health Sciences & Technology
Background & Interests
Low Braü
Medicine
Technology
Too Many Cooks
Biography
Ben is a postdoc in the Shalek Lab interested in applying single-cell genomics to improve cellular models of human disease and identify new drug targets and therapeutics. Ben’s research harnesses adult stem cell-derived organoids, particularly from the gastrointestinal tract to advance these next-generation cell models, and has focused on applying these models to inflammatory bowel disease.
Ben spent the first ~22 years of his life in and around Boulder, Colorado, including undergrad in Chemical & Biological Engineering at the University of Colorado Boulder. Deciding that 300+ days of sunshine and a culture of ‘work-life balance’ just wasn’t for him, he moved to Boston and embarked on PhD studies with Jeff Karp (Brigham & Women’s Hospital, Harvard Medical School) and Robert Langer (MIT) through the Harvard-MIT Health Sciences & Technology Program. In addition to research, Ben has a persistent entrepreneurial ‘itch’, including stints with the life sciences venture creation firm, Flagship Pioneering, and the Karp & Langer-founded biotech Frequency Therapeutics. When he’s not thinking about science or startups, Ben enjoys spending time with wife, traveling, and taking in the great outdoors.
Publications
Scalable, compressed phenotypic screening using pooled perturbations
Biology
Cancer
Immunology
Microbiology
R&D
Technology
Alex K. Shalek
Ben Mead
Conner Kummerlowe
Ivy Liu
Manny Guzman
Sarah Ingabire
Sergio Triana
Walaa Kattan
Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival
Biology
Alex K. Shalek
Ben Mead
Constantine Tzouanas
Evelyn Yuzhou Tong
Jay Prakadan
Kellie Kolb
Michelle Ramseier
Tyler Dao
Compressed phenotypic screens for complex multicellular models and high-content assays
Biology
Cancer
Chemistry
Computational Methods
Genomics
R&D
Statistics
Technology
Alex K. Shalek
Ben Mead
Conner Kummerlowe
Ivy Liu
Peter Winter
Thomas Nok Hin Cheng
Walaa Kattan
Cellular and transcriptional diversity over the course of human lactation
Biology
Cell Atlas
Genomics
Immunology
Medicine
Alex K. Shalek
Ben Mead
Brittany Goods
Kellie Kolb
Patricia Gao
Riley Drake
Sarah Nyquist
Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation
Biology
Computational Methods
Genomics
Immunology
Medicine
R&D
Technology
Alex K. Shalek
Ben Mead
Conner Kummerlowe
José Ordovas-Montañes
Marko Vukovic
Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes
Genomics
R&D
Technology
Alex Genshaft
Alex K. Shalek
Andrew Navia
Ben Mead
Carly Ziegler
Constantine Tzouanas
High-throughput organoid screening enables engineering of intestinal epithelial composition
Biology
Genomics
Medicine
R&D
Technology
Alex K. Shalek
Ben Mead
José Ordovas-Montañes
Marko Vukovic
SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
Biology
Cell Atlas
Genomics
Immunology
Infectious Disease
Statistics
Ben Mead
Benjamin Doran
Carly Ziegler
Constantine Tzouanas
James Gatter
Marc Wadsworth II
Marko Vukovic
Sam Allon
Sarah Nyquist
Vincent Miao
Spatially-resolved live cell tagging and isolation using protected photoactivatable cell dyes
Biology
Cancer
Chemistry
Genomics
R&D
Technology
Alex Genshaft
Alex K. Shalek
Andrew Navia
Ben Mead
Carly Ziegler
Constantine Tzouanas
Loss of DNA methyltransferase activity in primed human ES cells triggers increased cell-cell variability and transcriptional repression
Biology
Genomics
Alex K. Shalek
Ben Mead
Marc Wadsworth II
Riley Drake
Sam Allon