Marc Wadsworth II

Marc Wadsworth II

Former Graduate Student

Marc Wadsworth II

CV

Degrees & Affiliations

BS, Chemistry - Miami University (Ohio) PhD Candidate, Chemistry - MIT

Background & Interests

Biography

Marc Wadsworth is a Chemistry PhD candidate in the Shalek Lab. His research interests focus on developing and implementing single-cell technologies to study infectious disease. Currently, Marc is applying these new tools to study the infectious ecosystems of M. Tuberculosis and HIV. He received his Bachelor of Science in Chemistry from Miami University in Oxford, Ohio. In addition to research, Marc enjoys teaching and is currently a teaching assistant for 5.07, Biological Chemistry I. When not in lab, he enjoys playing the piano, practicing jiu-jitsu, and cooking with his wife.

Publications

Single-cell and spatial profiling highlights TB-induced myofibroblasts as drivers of lung pathology

Mbano. et al.,
Journal of Experimental Medicine,
2026

Tobacco smoke exposure recruits inflammatory airspace monocytes that establish permissive lung niches for Mycobacterium tuberculosis

Corleis et al.,
Science Translational Medicine,
2023

CD8+ lymphocytes are critical for early control of tuberculosis in macaques

Winchell et al.,
Journal of Experimental Medicine,
2023

PI3K activation allows immune evasion by promoting an inhibitory myeloid tumor microenvironment

Collins et al.,
Journal for Immunotherapy of Cancer,
2023

Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation

Kummerlowe et al.,
Science Translational Medicine,
2022

Multimodal profiling of lung granulomas in macaques reveals cellular correlates of tuberculosis control

Gideon et al.,
Immunity,
2022

A single-cell liver atlas of Plasmodium vivax infection

Mancio-Silva et al.,
Cell Host & Microbe,
2022

Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states

Song et al.,
Nature Communications,
2022

Genomic and transcriptomic correlates of immunotherapy response within the tumor microenvironment of leptomeningeal metastases

Prakadan et al.,
Nature Communications,
2021

The cellular architecture of the antimicrobial response network in human leprosy granulomas

Ma et al.,
Nature Immunology,
2021