Alex Genshaft

Alex Genshaft

Former Postdoctoral Fellow

Degrees & Affiliations

BS, Chemistry, Physics, & Biophysics - University of Pennsylvania MS, Chemistry - University of Pennsylvania PhD Candidate, Chemistry - MIT

Background & Interests

Biology Biology
Chemistry Chemistry
Computational Methods Computational Methods
Genomics Genomics
Getting Swole Getting Swole
Hot Stuff Hot Stuff
I Want a Hot Body, but I also Want Tacos I Want a Hot Body, but I also Want Tacos
Immunology Immunology
Keeping the Lab Humble Keeping the Lab Humble
R&D R&D
Statistics Statistics
Technology Technology

Biography

Alex S. Genshaft is a 5th year graduate candidate in the Shalek Lab interested in how communication between cells leads to changes systems-level behaviors. His research focuses on developing tools to probe the intra- and intercellular circuits that drive emergent phenotypes.

 

Alex grew up in Brooklyn, NY where he learned life’s most important facts like who makes the best pizza slice and how to ride the subway. After 18 years in the best city in the world, he moved to Philadelphia, PA to attend the University of Pennsylvania as a Vagelos Scholar in Molecular Life Sciences. There, he worked with Professor David W. Christianson studying terpene synthases and protein structure. He later graduated with B.A.s in Chemistry, Physics, and Biophysics and a M.S. in Chemistry. After college, he moved to Cambridge, MA to enroll in a Ph.D. program at the Department of Chemistry at MIT and work with Alex Shalek.

Publications

Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients
Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients
  • Genshaft et al.,
  • Hepatology,
  • 2023
Biology Biology
Cell Atlas Cell Atlas
Genomics Genomics
Immunology Immunology
R&D R&D
Technology Technology
Alex Genshaft Alex Genshaft
Alex K. Shalek Alex K. Shalek
Constantine Tzouanas Constantine Tzouanas
Ira Fleming Ira Fleming
Jasmin Joseph-Chazan Jasmin Joseph-Chazan
Mike Vilme Mike Vilme
Nancy Tran Nancy Tran
Riley Drake Riley Drake
Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversity
Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversity
  • Genshaft et al.,
  • bioRxiv,
  • 2021
Biology Biology
Cell Atlas Cell Atlas
Computational Methods Computational Methods
Genomics Genomics
Immunology Immunology
Infectious Disease Infectious Disease
R&D R&D
Technology Technology
Alex Genshaft Alex Genshaft
Alex K. Shalek Alex K. Shalek
Constantine Tzouanas Constantine Tzouanas
Ira Fleming Ira Fleming
Jasmin Joseph-Chazan Jasmin Joseph-Chazan
Mike Vilme Mike Vilme
Nancy Tran Nancy Tran
Riley Drake Riley Drake
Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes
Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes
  • Genshaft et al.,
  • Nature Communications,
  • 2021
Genomics Genomics
R&D R&D
Technology Technology
Alex Genshaft Alex Genshaft
Alex K. Shalek Alex K. Shalek
Andrew Navia Andrew Navia
Ben Mead Ben Mead
Carly Ziegler Carly Ziegler
Constantine Tzouanas Constantine Tzouanas
Spatially-resolved live cell tagging and isolation using protected photoactivatable cell dyes
Spatially-resolved live cell tagging and isolation using protected photoactivatable cell dyes
  • Genshaft et al.,
  • bioRxiv,
  • 2020
Biology Biology
Cancer Cancer
Chemistry Chemistry
Genomics Genomics
R&D R&D
Technology Technology
Alex Genshaft Alex Genshaft
Alex K. Shalek Alex K. Shalek
Andrew Navia Andrew Navia
Ben Mead Ben Mead
Carly Ziegler Carly Ziegler
Constantine Tzouanas Constantine Tzouanas
Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction
Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction
  • Genshaft et al.,
  • Genome Biology,
  • 2016
Biology Biology
Chemistry Chemistry
Genomics Genomics
R&D R&D
Technology Technology
Alex Genshaft Alex Genshaft
Alex K. Shalek Alex K. Shalek
Carly Ziegler Carly Ziegler
Jay Prakadan Jay Prakadan
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
  • Tirosh et al.,
  • Science,
  • 2016
Biology Biology
Cancer Cancer
Genomics Genomics
Medicine Medicine
Aleth Gaillard Aleth Gaillard
Alex Genshaft Alex Genshaft
Alex K. Shalek Alex K. Shalek
Carly Ziegler Carly Ziegler
Jay Prakadan Jay Prakadan
Kellie Kolb Kellie Kolb
Marc Wadsworth II Marc Wadsworth II
Sam Kazer Sam Kazer
Travis Hughes Travis Hughes
A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages
A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages
  • Kimmerling et al.,
  • Nat. Commun.,
  • 2016
Biology Biology
Genomics Genomics
Immunology Immunology
R&D R&D
Technology Technology
Alex Genshaft Alex Genshaft
Alex K. Shalek Alex K. Shalek
Sam Kazer Sam Kazer