Ira Fleming

Former Research Associate

Degrees & Affiliations

BA, Molecular Biology - Pomona College

Background & Interests

Biography

Ira Fleming is a research technician in the Shalek lab working on producing and analyzing RNA-sequencing data as a lens for the study of infectious disease. He received his B.A. in Molecular Biology from Pomona College in 2018 and moved Eastward, away from SoCal and his home in Seattle. Ira also loves to run, hike, and play music that he composes based on gene sequences on his cello.

Publications

Pro-inflammatory feedback loops define immune responses to pathogenic Lentivirus infection

Wilk et al.,
Genome Medicine,
2024

Single-cell RNA sequencing of liver fine-needle aspirates captures immune diversity in the blood and liver in chronic hepatitis B patients

Genshaft et al.,
Hepatology,
2023

Pro-inflammatory feedback loops define immune responses to pathogenic lentivirus infection

Wilk et al.,
bioRxiv,
2023

Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation

Kummerlowe et al.,
Science Translational Medicine,
2022

Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversity

Genshaft et al.,
bioRxiv,
2021

Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells

Jiang et al.,
JCI Insight,
2021

Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation in severe disease

Kummerlowe et al.,
bioRxiv,
2021

Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieu

Goods et al.,
JCI Insight,
2021

Functional compensation precedes recovery of tissue mass following acute liver injury

Walesky et al.,
Nature Communications,
2020

Inflammasomes within hyperactive murine dendritic cells stimulate long-lived T cell-mediated anti-tumor immunity

Zhivaki et al.,
Cell Reports,
2020