Toby Aicher

Former Research Associate

CV

Degrees & Affiliations

BA, Molecular Biology and Biochemistry - Middlebury College

Background & Interests

Biography

Toby Aicher is a research technician in the Shalek and the Walker labs who uses single-cell RNA-sequencing to investigate how the immune system responds to acute HIV infection in elite controllers and chronic progressors. His interests include developmental trajectories of lymphocytes, functional heterogeneity among cytotoxic T-cells, and epigenomics.

Toby grew up in Maine and attended college in Vermont. He has a B.A. in Molecular Biology and Biochemistry from Middlebury College. In his free time Toby likes swimming, amateur astronomy, and exploring Boston.

Publications

Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation

Kummerlowe et al.,
Science Translational Medicine,
2022

Integrated single-cell analysis of multicellular immune dynamics during hyperacute HIV-1 infection

Kazer et al.,
Nature Medicine,
2020

Induction of metabolic quiescence defines the transitional to follicular B cell switch

Farmer et al.,
Science Signaling,
2019

Integrated Single-Cell Analysis of Multicellular Immune Dynamics during Hyper-Acute HIV-1 Infection

Kazer S.W. et al.,
bioRxiv,
2019

Seq-Well: A Sample-Efficient, Portable Picowell Platform for Massively Parallel Single-Cell RNA Sequencing

Aicher et al.,
Single-Cell Methods,
2019

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

Roider et al.,
frontiers in Immunology,
2018